中药灌肠对慢性肾衰竭临床研究

Clinical Research on Effect of Traditional Chinese Medicine Enema in the Treatment of Chronic Renal Failure

目的:观察自拟排浊汤治疗慢性肾衰竭的疗效及其机制探讨。方法:将患者80例随机分为治疗组和对照组各40例,治疗组予以自拟排浊汤治疗,对照组予以低脂低蛋白饮食,根据病情予降压、抗感染、维持水电解质酸碱平衡、适当利尿消肿及一般对症治疗;检测各组血肌酐(Scr)、尿素氮(BUN)、甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白(HDL)、低密度脂蛋白(LDL)、血尿酸(BUA)。结果:治疗组和对照组总有效率分别90%和65%,差异有统计学意义(P<0.05);在降低Scr、BUN、TG、TC、LDL、BUA方面治疗组均优于对照组,差异有统计学意义(P<0.05)。结论:自拟排浊汤治疗慢性肾衰竭疗效优于单用西药治疗组。

Objective： To observe the effect of enema with Traditional Chinese Medicine（TCM） in chronic renal failure. Methods： 80 cases with chronic renal failure（CRF） were divided into two groups randomly,the study group and the control group. To compare the two different groups with Scr, BUN ,TG, TC, HDL, LDL, BUA between pre - treatment and post -treatment. Results： Enema with TCM could decrease the data of Scr,BUN,TG,TC,LDL,BUA, and P value of less than 0.05 was considered to be statistically significant（ P 〈 0.05 ）. Conclusion： Enema with TCM is effective in treatment of CRF.