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大肠埃希菌Ⅰ类整合子遗传标记研究 被引量:5

Study on the genetic marker of class 1 integron in Escherichia.coli
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摘要 目的了解我院大肠埃希菌(ECO)的Ⅰ类整合子遗传标记qacE△1-sull基因存在状况。方法对临床分离的34株ECO菌,采用PCR方法检测Ⅰ类整合子遗传标记qacE△1-sull基因。结果34株ECO菌qacE△1-sull基因阳性有28株(82.4%)。结论本组34株ECO菌药敏实验显示,β-内酰胺酶和氨基糖苷类抗生素耐药性高与Ⅰ类整合子遗传标记qacE△1-sull基因高检出率有关。 Objective To investigate the class 1 integron genetic marker (qacE△1-sull gene) of Escherichia.coli in our hospital. Methods Thirty-four strains of Escherichia.coli were isolated from hospitalized patients, and the class 1 integron genetic marker(qacE△1-sull gene) were analyzed by polymerase chain reaction. Results Among Thirty-four strains of Escherichia.coli, The qacE△1-sull gene expression was detected in twenty-eight strains (82.4%). Conclusions The antimicrobial susceptibility test performed in thirty-four strains of Escherichia.coli indicated that, the high resistance of β-lactam antibiotics and aminoglycoside antibiotics was concerned with the high isolating rate of class l integron genetic marker qacE△1-sull gene.
出处 《世界感染杂志》 2008年第2期113-114,127,共3页 World Journal of Infection
关键词 大肠埃希菌 整合子 基因 Escherichia.coli integron gene
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  • 1顾兵,童明庆,刘根焰,倪芳,赵旺胜,梅亚宁,文怡,魏源华,黄珮珺,潘世扬.整合子介导大肠埃希菌和克雷伯菌多重耐药机制的研究[J].中华检验医学杂志,2006,29(8):725-729. 被引量:28
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