阿罗洛尔——无代谢不良反应的肾上腺素β受体阻滞药

Arotinolol:a adrenergic beter-blocker without adverse reactcion on metabolism

阿罗洛尔除具有肾上腺素α、β受体阻滞药共有的抑制交感及扩张血管特点外,在减慢心率作用方面比常用的卡维地洛、拉贝洛尔明显,与肾上腺素β受体阻滞药美托洛尔相近,但无美托洛尔的糖、脂代谢不良反应。在降压方面,尤其适用于中青年舒张期高血压,能有效地减慢心率、降舒张压。

Arotinolol demonstrates a common effect of inhibiting sympathetic excitement and dilating the blood vessel which is owned by alpha/beta-adrenergic blocker. In addition to that, it also can lower the heart rate （HR） significantly comparing to carvedilol or labetalol. The effect of HR lowering is close to beta-blocker, metoprolol, without the adverse reactions on glucose and lipid metabolism. In the treatment of hypertension, arotinolol is particularly applicable to middle-aged diastolic hypertension and has effective in slowing HR and lowering the diastolic blood pressure.