摘要
泡腾技术作为加快制剂崩解,促进药物溶出的技术,常用于速释制剂中,随着相关技术与理论研究深入,泡腾技术越来越广泛应用于缓控释制剂和脉冲释药系统中,调节释药制剂行为。作者主要介绍了泡腾技术在泡腾片、胃漂浮制剂、渗透泵片和脉冲释药系统中研究应用,以及泡腾制剂共性关键技术研究进展,有利于泡腾制剂研究与开发。
Effervescent technique, which can accelerate drug disintegration and dissolution, is usually applied in quick release preparations. Along with the development of pharmaceutical technique and theory, effervescent technique is used more and more extensively to adjust the behavior of drug release, such as in sustained and controlled release preparations, pulsatile drug delivery systems, and so on. This review demonstrated the new applying of effervescent technique in effervescent tablets, stomach floating forms, osmotic pump tablets and pulsatile drug delivery systems, adding to the critical common technique of effervescent forms in drug research. This will be benefit for the further research and development of effervescent technique.
出处
《中国中药杂志》
CAS
CSCD
北大核心
2008年第8期973-976,共4页
China Journal of Chinese Materia Medica
基金
国家科技支撑计划项目(2006BA109B07-06)
关键词
泡腾技术
泡腾片
胃内漂浮制剂
渗透泵片
脉冲释药制剂
effervescent technique
effervescent tablets
stomach floating forms
osmotic pump tablets
pulsatile drug delivery systems
