3Grunebaum E, Roifma CM. Gene abnormalties in patients with hemophagocytic lymphohistiocytosis[ J]. Isr Med Assoc J,2002,4(5 ) : 366-369.
4Stepp SE, Dufourcq-Lagelouse R, Le Deist F,et al. Perforin gene defects in familial hemophagocytic lymphohistiocytosis [ J ]. Science, 1999,286 (5446) : 1957-1959.
5Goransdotter-Edcson K, Fadeel B. Spectrum of perforin gene mutations in familial hemophagocytic lymphohistiocytosis[ J]. Am J Hum Gnent ,2001,68 ( 3 ) :590-597.
6Grunebaum E, Zhang J, Dadi H, et al. Haemophagocytic lymphohistiocytosis in X-linked severe combined immunodeficiency [ J ]. Br J Haematol,2000,108 (4) :834-837.
7Arico M, Imashuku S, Clementi R, et al. Haemophagocytic lymphohistiocytosis due to germline mutations in SH2DIA, the X-linked lymphoproliferative diease gene [ J ]. Blood, 2001, 97 ( 4 ) : 1131-1133.
8Reiner AP, Spivak JI. Hematophagie histiocytosis. A report of 23 new patients and a review of the literature[ J]. Medicine, 1988,67 (6) :369-388.
3Erduran E,,Gedik Y,Sen Y,et al.Successful treatment of reactive hemophagotcytic syndrome with cyclosporine A and intravenous immunoglobulin. Turkish Journal of Pediatrics . 2000
4Papo T,Andre MH,Amoura Z,et al.The spectrum of reactive hemophagocytic syndrome in systemic lupus erythematosus. The Journal of Rheumatology . 1999
5Kaito K,Kobayashi M,Katayama T,et al.Prognostic factors of hemophagocytic syndrome in adults: analysis of 34 cases. European Journal of Haematology . 1997
