植物RNA干扰的研究进展被引量：15

The progress of RNAi in plant

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摘要 RNA干扰(RNA interference,RNAi)是利用双链RNA(dsRNA)特异性地降解相应序列的mRNA,从而特异性地阻断相应基因的表达。在过去10年中,RNA干扰及相关沉默反应的机制研究取得了重大进展,RNAi也发展成为一种强有力的实验工具,用来控制目的基因的表达以获取预期的生物表型。详细综述了近年来RNA干扰机制方面的研究进展及RNA干扰在植物中的应用进展。 Introduction of double-stranded RNA（dsRNA） into cells can induce specific mRNA degradation, this process is called RNA interference（RNAi）. During the past 10 years, tremendous progress has been made in revealing the underlying mechanism of RNAi and related silencing responses. RNAi has become a powerful research tool in regulating the expression of target genes for expected or desirable phenotypes. In this article, the mechanism of RNAi has been described and summarized, and the application of RANi in plant functional genomics has also been reviewed.

作者马建刘艺苓王丕武

机构地区吉林农业大学生物技术中心

出处《中国油料作物学报》 CAS CSCD 北大核心 2008年第2期252-259,共8页 Chinese Journal of Oil Crop Sciences

基金国家转基因研究与产业化开发专项基金(ZY03-B-17-01)

关键词植物转录后基因沉默 RNA干扰 Plant PTGS RNAi

分类号 Q786 [生物学—分子生物学]

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