脑卒中后癫痫发作的发生率及其临床特点

Frequency and related factors of seizures in acute cerebral stroke

目的研究脑卒中后癫痫发作的发生率及其临床特点。方法回顾性分析1224例急性脑卒中患者发病后癫痫发作的发生率、发作类型、病死率、脑电图及癫痫与脑卒中类型、病灶部位的相关性。结果急性脑卒中发病后癫痫发作的发生率为5.56%,其中以蛛网膜下腔出血后癫痫发作的发生率最高(8.06%);早发性癫痫发作以全身性发作多见,迟发性癫痫发作以部分性发作为主;部分性发作多发生于缺血性卒中,而出血性卒中以全面性癫痫发作好发。无论病变性质如何,皮质损害的患者易导致癫痫发作。结论脑卒中后癫痫发作很常见,其发生率及预后与卒中类型及病变部位性质相关。

Objective To study the frequency and clinical features of seizure in acute cerebral stroke. Methods Clinical data of 1224 patients with acute cerebral stroke were investigated retrospectively. The frequency, classification , mortality and electroencephalogram of seizure were described, and its relation with the type of stroke and the location of lesion were analyzed. Results The frequency of seizure in all acute cerebral stroke was 5.56% and 8.06% in subarachnoid hemorrhage. Generalized seizures were common in early - onset seizures while partial seizures were common in late - onset seizures, And partial seizures were common in ischemia stroke while generalized seizures were common in hemorrhagic stroke. Seizures were more frequent in patients with cortical involvement whether in ischemic stroke or in hemorrhagic stroke. Conclusion Seizures are common in patients with acute cerebral stroke, Its frequency and prognosis relates with the type of stroke and the location of lesion.