摘要
目的探讨老年高血压病患者血压变异性(BPV)与左室肥厚的关系。方法选择216例高血压患者进行24 h动态血压监测(ABPM)和超声心动图检查,分析血压变异性与左室肥厚的关系。结果老年高血压患者合并左室肥厚组与无左室肥厚组比较,年龄、性别、24 h平均血压和血糖、血脂水平无显著差异,但左室肥厚组的24 h收缩压变异性(16.8±1.9 vs 14.3±2.3),白昼(14.9±2.5 vs 13.8±2.4)和夜间(10.8±3.7 vs 9.7±2.9)收缩压变异性均显著大于无左室肥厚组(P<0.05)。结论老年高血压患者收缩压波动与左室肥厚密切相关,可能预测高血压靶器官损害和不良心血管事件。
Objective To explore the relationship between blood pressure variability and left ventricular hypertrophy in elderly hypertensive patients. Methods The ambulatory blood pressure monitoring and eehocardiography were performed in 216 hypertensive paitents. Results There is no difference in clinical characteristic of age, gender, 24-hour mean blood pressure, fasting blood glucose, and blood cholesterol between patients with and without left ventricular hypertrophy. However, systolic blood pressure variability of 24hours (16.8 ± 1.9 vs 14.3 ±2.3), days (14.9 ±2.5 vs 13.8 ±2.4)and nights(10.8 ±3.7 vs 9.7 ± 2.9) were significantly higher in patients with left ventricular hypertrophy than those without left ventricular hypertrophy. Conclusion Systolic blood pressure variability may be associated with left ventricular hypertrophy and predict the target organ damage and adverse cardiovascular events in hypertensive patients.
出处
《中国分子心脏病学杂志》
CAS
2008年第4期233-235,共3页
Molecular Cardiology of China
关键词
高血压
血压变异性
左室肥厚
Hypertension
Blood pressure variability
Left ventricular hypertrophy