摘要
肠道病毒71型(EV71)是引起手足口病的重要病原,能引发严重的神经系统并发症甚至死亡,构成严重的危害,但目前对EV71尚无有效的抗病毒治疗策略。此文就抗EV71的药物、疫苗及RNA干扰技术的研究进展作了综述,为EV71的防治工作提供借鉴。
Enterovirus 71(EV71)is a highly infectious major causative agent of hand-foot-mouth disease, which could lead to severe neurological complications and high mortality levels. Currently, there is no effective antiviral therapy against EV71 infections. This paper reviews about the antiviral drug, vaccine and RNA interference strategy which were exploited to treat the infection of EV71.
出处
《国际流行病学传染病学杂志》
CAS
2008年第4期262-265,共4页
International Journal of Epidemiology and Infectious Disease
基金
浙江省科技厅重大项目(2007F30014)
浙江省自然科学基金人才培养项目(R204306)
关键词
手足口病
肠道病毒71型
治疗
疫苗
RNA干扰
Hand, foot and mouth disease
Entemvirus 71
Therapy
Vaccine
RNA interference