摘要
糖尿病视网膜病变(DR)是糖尿病最严重和常见的微血管慢性并发症之一,其发病机制复杂,至今尚未完全阐明。大量资料表明,炎症参与了糖尿病视网膜病变的发生、发展,非甾体抗炎药(NSAIDs)通过抑制炎症因子或炎症介质的表达,控制视网膜炎症反应,可以减轻DR视网膜的损伤。如今,NSAIDs已经成为研究药物治疗DR的热点之一。
Diabetic retinopathy（DR） is the most common and severe long - term microvascular complication of diabetes mellitus（DM） ,one of four reasons leading to blindness at present. The pathogenesis of DR is complicated and has not been completely illuminated. The mass data manifest that the inflammation is involved in the occurrence and development of DR. NSAIDs can control retinal inflammation and lessen retinal lesion of DR through inhibiting the expression of inflammatory factors and mediators of inflammation. Nowadays treating DR with non-steroidal anti-inflammatory drugs has become one hot topic to study and research DR.
出处
《中国药理学通报》
CAS
CSCD
北大核心
2008年第9期1124-1127,共4页
Chinese Pharmacological Bulletin
基金
香港保健协会资助项目(No20060906)
