高血压患者血压变异性临床分析

Clinical analysis of blood pressure variability in hypertensive patients

目的探讨高血压病人血压变异的特点与高血压靶器官损害的关系。方法选择高血压病人Ⅰ期50例,Ⅱ期44例和血压正常人26例进行动态血压检测。结果高血压组血压变异各参数均显著大于正常组。三组间血压变异相同,白天增高夜间下降,收缩压变异大于舒张压变异。Ⅱ期高血压组血压变异各参数显著大于Ⅰ期高血压组。结论血压变异增大是高血压患者的一个重要临床特征,血压变异增大与靶器官损害有关。

Objective To evaluate the characteristics of blood pressure variability （BPV） and relationship beween BPV and target organ in hypertensive patients. Methods 50 patients with stage Ⅰ, 44 patients with stage Ⅱ and 26 normal controls were undergone 24 hours ambulatory blood pressure monitoring. Results The parameters of BPV in patients with hypertension were significantly higher than those in normal controls. The increased BPV in daytime and decreased BPV at nighttime were all observed in three groups. Systolic BPV was higher than diastolic BPV. The parameters of BPV in stage Ⅱ were obviously higher than those in stage Ⅰ. Conclusion It＇s suggested that the increased BPV is a important clinical features for hypertension. Which is relevant to the target organ damage.