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PPARγ对脂类代谢和脂肪细胞分化的调控 被引量：16

Regulation of PPARγ on Lipid Metabolism and Adipocyte Differentiation
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摘要 过氧化物酶体增殖物激活受体γ是一种配体活化的核转录因子,具有多种生物学效应。除能调节脂肪细胞分化、脂代谢,细胞增殖、细胞周期外,还能调控细胞因子生成,增强机体对胰岛素的敏感性等作用。主要就PPARγ对脂类代谢和脂肪细胞分化调控作用的最新研究进展进行综述。 Peroxisome proliferator-activated receptor-γ is a transcriptional factor that is activated by its ligands. PPARγ has numerous biology functions and can regulate numerous processes, including adipocyte differentiation, lipid metabolism, cell proliferation and cell cycle. In addition, it can also control the production of cell factors and improve insulin sensitivity. This review summarized the latest developments of the functions of PPARγ in relating to lipid metabolism and adipocyte differentiation.
作者 宋新磊 王静 崔焕先 高士争
机构地区 云南农业大学云南省动物营养与饲料重点实验室
出处 《云南农业大学学报（自然科学版）》 CAS CSCD 2008年第6期851-855,872,共6页 Journal of Yunnan Agricultural University:Natural Science
基金 国家自然科学基金(30660132) 云南省自然科学重点基金(2005C0008Z)
关键词 PPARΓ 脂类代谢 脂肪细胞分化 PPARγ lipid metabolism adipoeyte differentiation
分类号 Q54 [生物学—生物化学]
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参考文献43

  • 1[1]ZHANG X,HOWARD A.PPAR and Immune SystemWhat Do We Know?[J].International Immunopharmacology,2002,2 (8):1029-1044.
  • 2[2]DAVID KM,RUBIN CJ,PHARIS M,et al..Improvement of Giycemic Control,Triglycefides,and HDL Cholesterol Levels With Muraglitazar,a Dual (α/γ) Peroxisome Proliferator-Activated Receptor Activator,in Patients With Type 2 Diabetes Inadequately Controlled With Mefformin Monotherapy[J].DIABETES CARE,2006,29:1016-1023.
  • 3[3]PHILIPPE L,GIULIA C,FRUCHART J C,et al..Sorting out the Roles of PPARα in Energy Metabolism and Vascular Homeostasis[J].The Journal of Clinical Investigation,2006,116 (3):571 -580.
  • 4[4]BLANQUERT C,BARBIER O,FRUCHART JC,et al..Peroxisome Proliferator-activated Receptors:Regulation of Transcriptional Activities and Roles in Inflammation[J].The Journal of Steroid Biochemistry and Molecular Biology,2003,85 (2-5):267-273.
  • 5[5]YOUSSEF J,BADR M.Role of Peroxisome Proliferatoractivated Receptors in Inflammation Control[J].Journal of biomedicine ＆ biotechnology,2004,(3):156-166.
  • 6[6]TERAUCHI Y,KADOWAKI T.PPAR and Diabetes[J].Nippon Rinsho,2005,63 (4):623 -629.
  • 7[7]TAKADA 1,KATO S.PPARs Target Genes[J].Nippon Rinsbo,2005,63 (4):573 -577.
  • 8[8]YANG XY,WANG LH,CHEN T,et al..Activation of Human T Lymphocytes is Inhibited by Peroxisome Proliferator-activated Receptor-γ (PPARγ) Agonists:PPARγ/ co-association with Transcription Factor NFAT[J].The Journal of biological chemistry,2000,275(7):4541 -4544.
  • 9[9]TAKAHASHI N,GOTO T,KUSUDO T et al..The Structures and Functions of Peroxisome Proliferator-activated Receptors (PPARs)[J].Nippon Rinsho,2005,63 (4):557-564.
  • 10[10]TAKAHASHI S,TANAKA T,KODAMAT,et al..Peroxisome Proliferator-activated Receptor Delta (PPARdeita),a Novel Target Site for Drug Discovery in Metabolic Syndrome[J].Pharmacological research,2006,53(6):501 -507.

同被引文献200

引证文献16

二级引证文献49

云南农业大学学报（自然科学版）
2008年 第6期

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