摘要
目的:了解和分析我院药品不良反应(ADR)的发生特点和一般规律,为临床合理用药提供信息,为深入开展ADR监测工作提供依据。方法:对我院2006年11月～2007年11月收集并上报的194例ADR报告进行分类统计分析。结果:194例ADR报告中,21～60岁患者ADR的发生率最高(63.9%),且13例严重ADR就有11例发生在此年龄阶段(84.6%);涉及的药品42种,以抗感染药物引起的ADR例数占首位(69.1%);报告者主要来源于护士(91.2%);主要的ADR类型为皮肤及附件损害(51.0%)。结论:应重视临床ADR的监测,加强监测上报人员的培训工作,推进临床合理用药,保障患者用药安全。
OBJECTIVE ： To investigate and analyze the characteristics and the regular pattern of adverse drug reactions （ADRs） in our hospital for reference of rational use of drugs and further development of ADR monitoring. METHODS： A total of 194 ADR cases collected and reported in our hospital from Nov. 2006 to Nov. 2007 were classified and analyzed statistically. RESULTS： Of the 194 ADR cases, 63.9% were seen in patients aged from 21 to 60, and 11 of a total of 13 serious ADR cases occurred in this group （84.6%）. The drugs that induced ADR totaled 42 kinds, with anti-infectives showing the highest proportion （69. 1% ）. Most （91.2%） of the cases were reported by nurses. The main presentation of the ADR was lesions of skin and its appendages. CONCLUSION： It is necessary to intensify ADR monitoring and training of staff on ADR reporting in order to promote rational drug use in the clinic and ensure patients＇ medication safety.
出处
《中国医院用药评价与分析》
2008年第11期871-872,共2页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
药品不良反应
统计
分析
合理用药
Adverse drug reactions
Statistics
Analysis
Rational use of drugs
