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脑钠肽检测的临床应用进展 被引量:12

Progression of brain natriuretic peptide testing in clinical application
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摘要 脑钠肽(BNP)有利钠、利尿、扩张血管及松弛平滑肌作用和对抗心室重塑,减少心肌肥厚和心室扩大的作用。BNP血浆浓度是监测许多疾病发生、发展、预后的一项良好指标,尤其在心血管疾病。检测血浆BNP水平是心肺疾病鉴别诊断,心血管疾病诊断和评估疗效、预后以及指导改善预后的重要指标。 Brain natriuretic peptide causes natriuresis, diuresis, vaso-dilatation, smooth muscle relaxation, antifibrotic effects on cardiac fibroblasts, impairment myocardial hypertrophy and enlarged ventricle. Plasma concentrations of BNP is a good marker of later development and prognostic of kinds of diseases, especially cardiovaseular disease. The role of BNP is recommended as the key examination to exclude, reveal the pulmonary disease. In the management of patients with cardiovascular disease the role of BNP in the diagnosis, management and prognosis is evident.
作者 陈玲 曹颖平
出处 《国际内科学杂志》 CAS 2008年第12期730-734,共5页 International Journal of Internal Medicine
关键词 脑钠肽 心脏重构 心血管疾病 Brain natriuretic peptide Cardiac remodeling Cardiovascular disease
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