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心理干预对白癜风患者心理状况及5-羟色胺和去甲肾上腺素水平影响的研究 被引量:7

The effect of psychological intervention on the psychological state,5-HT and NE in the patients with vitiligo
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摘要 目的:对白癜风患者实施心理干预,了解其干预前后的心理状况及5-羟色胺和去甲肾上腺素水平的变化。方法:采用心理健康症状自评量表(SCL-90)、汉密尔顿抑郁量表(HAMD)以及汉密尔顿焦虑量表(HAMA)调查患者干预前后心理状况的变化,及检测患者外周血中5-羟色胺(5-HT)和去甲肾上腺素(NE)水平的变化。结果:SCL-90测评显示白癜风组在躯体化、人际关系、焦虑、抑郁和敌对性项的评分明显高于对照组,差异有统计学意义(P<0.05);干预后评分较干预前明显下降,差异有统计学意义(P<0.05)。HAMD、HAMA测评显示:白癜风组得分明显高于对照组,差异有统计学意义(P<0.05);干预后评分较干预前明显下降,差异有统计学意义(P<0.05)。白癜风患者接受心理干预后,5-HT和NE水平比治疗前显著上升(均P<0.05)。结论:白癜风患者可能存在多方面心理障碍,心理干预对其可能有一定的治疗作用。 Objective:To investigate the influence of psychological intervention on psychological state, 5 -HT and NE in the patients with vitiligo. Methods: SCL -90, HAMD and HAMA were used to investigate the psychological state of the vitiligo patients group and the control group before and after psychological intervention. At the same time, the blood levels of 5 - HT and NE were also measured. Results: Scores of somatization, interpersonal sensitivity, depression, anxiety and hostility of the patients with vitiligo in SCL - 90 were higher than those of controls, and the difference was significant ( P 〈 0. 05 ) ; After intervention, the scores were significantly decreased (P 〈 0. 05). Scores of HAMD and HAMA of the patients with vitiligo were higher than those of controls, and the difference was significant (P 〈 0. 05 ). After treatment, the scores decreased significantly ( P 〈 0. 05 ). The levels of 5 - HT and NE increased significantly after psychological intervention (P 〈 0.05 ). Conclusion: Patients with vitiligo might have some psychological disorders, and psychological intervention was helpful.
出处 《岭南皮肤性病科杂志》 2008年第6期320-323,共4页 Southern China Journal of Dermato-Venereology
关键词 白癜风 心理干预 5-羟色胺 去甲肾上腺素 vitiligo psychological intervention 5 - HT NE
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参考文献11

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