摘要
轻度认知功能障碍是认知功能障碍发展的过渡阶段,通过对载脂蛋白E(apoE)及其基因多态性与痰瘀证、高脂血症、MCI间相关性的分析认为,痰瘀证是MCI发病的重要病机,MCI痰瘀证与apoE等位基因ε4间存在密切相关性,血脂代谢紊乱可能是其中的重要环节。
Mild Cognitive Impairment (MCI)is a transitional stage during the progress of cognitive Impairment. Through the analysis of the relativity of apolipoprotein E (apoE), apoE genetic polymorphism, phlegm stagnation and blood stasis, hyperlipernia and MCI, we got this conclusion: syndrome of phlegm stagnation and blood stasis is an important underlying pathogenesis of MCI; the syndrome of phlegm stagnation and blood stasis has a close relation to apoFε4 allele, and lipid-metabolism disturbance is a key link to this relation.
出处
《国际中医中药杂志》
2009年第1期75-76,共2页
International Journal of Traditional Chinese Medicine
关键词
轻度认知功能障碍
痰瘀证
载脂蛋白E
高脂血症
Mild Cognitive Impairment
Phlegm Blood Stasis
apolipoprotein E
hyperlipemia