高血压病患者动脉弹性与中医辨证分型的相关性研究

Study on the Relationship between Arterial Compliance and Syndrome Differentiation Typing in Hypertensive Patients

目的探讨高血压病患者动脉弹性与中医辨证的相关性及其对治疗、预后的价值。方法采用HDI CVProfilor DO-2020无创动脉功能检测仪(美国HDI公司)对342例高血压病患者进行大、小动脉弹性指数(C1,C2)测定,同时采集病史,查体及作有关血生化指标。结果与肝火上炎组、痰湿壅盛组比较,阴虚阳亢、阴阳两虚组的C1,C2均明显降低(P<0.05)。结论动脉弹性检查可为高血压病患者病情判断,辨证论治提供客观证据,对中医临床辨证分型有一定价值。

Objective To inquire into the relationship between arterial compliance and TCM syndrome differentiation and discuss the indicative values of treatment and prognosis. Methods Using non - invasively obtained radial pulse contour analysis （ HDI CV Profilor DO -2020） , large and small arterial compliance （C1 and C2） of 342 patients with primary hypertension were measured. Meanwhile, the medical history, physical exam and biochemistry variables were collected. Results Compared with patients group with flaming - up of the liver fire syndrome and patient group with accumulation of phlegm - damp syndrome, the C1, C2 of patients group with hyperactivity of Yang due to Yin deficiency syndrome and Patients group with Yin - yang deficiency syndrome were significantly decreased （ P 〈 0.05 ）. Conclusion The examination of arterial elasticity is one of the objective evidence for judging state of illness and syndrome differentiation based on treatment in patients with essential hypertension. Thus, it shows definite referential importance to the TCM syndrome typing.