桂枝茯苓胶囊在不孕症治疗中的应用

Application of Guizhifuling capsules in the treatment of infertility

目的：探讨桂枝茯苓胶蠖在不孕症治疗中的临床效果。方法：对2003年1月-2007年12月就诊于我院门诊的不孕症患者117例（其中慢性盆腔炎42例，子宫肌瘤34例，子宫内膜异位症23例，多蠼卵巢综合症18例）作为观察对象，分别服用桂枝茯苓胶囊3—6个月，平均服用时间为4．57±1．86个月，服用方法为3次／d，3粒／次。追踪停药半年内的妊娠率。结果：慢性盆腔炎、子宫内膜异位症、子宫肌瘤和多瞧卵巢综合征的妊娠率分别为40．47％（17／42），34．78％（8／23），41．12％（14／34），33．34％（6／18）。其中慢性盆腔炎和子宫肌瘤的妊娠率高于子宫内膜异位症和多超卵巢综合征（P〈0．05）。结论：桂枝茯苓胶发可广泛应用于女性不孕症治疗中，尤其对于慢性盆腔炎和子宫肌瘤等原因所致不孕症可取得良好疗效。

Objective To investigate the clinical effect of Guizhifuling capsules in the treatment of infertility. Method Total 117 cases who visited in our hospital from January 2003 to December 2007 by infertility were observed, including 42 cases of chronic pelvic in- flammatory disease, 34 cases of uterine fibroids, 23 cases of endometriosis and 18 cases of polycystic ovary syndrome. All cases took Guizhifuling capsule 3 to 6 months, the average time of taking medication were （4.57 ± 1.86） months, the method was 3 capsules, three times a day. Then we tracked the pregnancy rate after stopping drag 6 months. Results Chronic pelvic inflammatory disease, endometriosis, uterine fibroids and polyeystic ovary syndrome in pregnancy rate were 40.47% （17/42）, 34.78% （8/23）, 41.12% （14/34） and 33.34% （6/18）. The pregnancy rate of chronic pelvic inflammatory disease and uterine fibroids were higher than endometriosis and polycystic ovary syndrome （ P 〈 0.05 ）. Conclusion Guizhifuling capsules can be widely used in the treatment of infertility. Moreover it can obtain good effect particularly in infertility by chronic pelvic inflammatory and uterine fibroids.