摘要
目的探讨腺苷脱氨酶(ADA)、C反应蛋白(CRP)、癌胚抗原(CEA)在胸腔积液中鉴别诊断的意义。方法收集已确诊的胸腔积液标本76例(结核性胸腔积液29例、癌性胸腔积液38例和化脓性胸腔积液9例),检测胸腔积液中ADA、CRP和CEA数值,并进行各组间统计学分析。结果ADA在结核性胸腔积液及化脓性胸腔积液明显升高,在癌性胸腔积液明显偏低(P<0.01)。CRP在化脓性胸腔积液升高最明显,在结核性胸腔积液次之,在癌性胸腔积液中值最低,三者之间比较有显著差异(P<0.01)。CEA在癌性胸腔积液中均值明显高于结核性胸腔积液和化脓性胸腔积液组(P<0.01)。结论ADA、CRP和CEA联合监测对胸腔积液的鉴别诊断有较好的意义。
Objective To explore differential diagnosis value of adenosine deaminase (ADA), C-reactive protein (CRP) and earciuoembryonic antigen (CEA) for pleural effusions. Methods 29 cases with tuberculous,38 cases wih malignant and 9 cases with empyema pleural effusions were enrolled into the study. ADA, CRP and CEA were tested in those cases. Results ADA activity in tuberculous and empyema pleural effusions was higher than malignant pleural effusions (P 〈 0. 01 ). CRP in empyema was significantly higher than others( P 〈 0. 01 ). CEA in malignant pleural effusions was significantly higher than others ( P 〈 0. 01 ). Conclusion ADA, CRP and CEA are useful parameters for differential diagnosis of pleural effusions.
出处
《临床肺科杂志》
2009年第3期313-314,共2页
Journal of Clinical Pulmonary Medicine