组织工程材料的表面改性研究及应用:等离子体改性和接枝改性(英文)

Surface modification of tissue-engineered materials:Plasma and grafting modification

组织工程材料的表面物理化学性质对材料的组织相容性有着重要影响。因而对材料的表面进行改性,在保持材料物理机械性能的前提下引入可促进细胞黏附和生长的基团或生物活性分子,可显著改善材料的细胞相容性。目前,细胞相容性聚合物的表面改性方法主要有:等离子体改性、接枝改性等方法。文章从等离子体改性、接枝改性等方面论述了组织工程材料的表面改性方法及其在组织工程中的应用。

Surface physical chemical properties of tissue-engineered materials are greatly important for histocompatibility of the materials. Therefore, surface modification based on original physical mechanical performance could promote cell attachment and growth or bioactive molecule, and significantly improve material cell compatibility. To date, plasma and grafting has become main methods of surface modification of polymers. This paper introduced plasma and grafting methods of surface modification of materials and the application in tissue engineering.