摘要
观察中药复方柴蔻冲剂(CKI)对慢性酒精性肝损伤大鼠的防护作用。CKI可显著提高红细胞和肝组织中超氧化物歧化酶(SOD)活性,血与肝组织中过氧化氢酶(CAT)、谷胱甘肽过氧化物酶(GSH-PX)的活性。显著降低血浆与肝组织中脂质过氧化终产物丙二醛(MDA)含量,抑制氧自由基的产生,提高组织抗氧化能力。并探讨了柴蔻冲剂的量效关系。
The liver-protective effect of a Chinese medical prescription,Chaikou granule was observed in rats with alcoholic liver injury.The result showed that Chaikou granule could obviously enhance activities of SOD,CATand GSHPX in the liver or in the blood,and reduce the MDA and free radicals in the plasma and liver,indicating the increase of antioxidation potency in tissue.
出处
《中国实验方剂学杂志》
CAS
1998年第2期28-30,共3页
Chinese Journal of Experimental Traditional Medical Formulae
基金
国家中医药管理局资助
关键词
柴蔻冲剂
酒精性肝损伤
抗脂质过氧化
Chaikou granule,alcoholic liver injury,lipid peroxidation