摘要
目的:通过对中药不良反应的回顾性分析,加深对中药不良反应的认识,为临床安全合理用药提供参考。方法:Excel电子表和手工筛选,对医院2004年1月～2007年10月收集的623例中药不良反应报告进行分类统计并分析。结果:不良反应可以发生在任何年龄段,因果关系评价中很可能居多,涉及ADR的药品剂型以注射剂居首位,用药途径以静脉滴注为主,主要的不良反应累及系统-器官及其临床表现为皮肤及其附件损害。结论:中药的ADR不容忽视,应合理使用注射剂,慎重选择静脉滴注给药治疗,以减少不良反应的发生。加快药品不良反应信息的传递,保障公众安全合理用药。
OBJECTIVE： To analyze the adverse drug reaction （ADR） induced by traditional Chinese medicines so as to deepen our understanding on this ADR and provide reference for clinical safe and rational medication. METHODS： 623 ADR cases induced by traditional Chinese medicines collected by Excel electronic forms and manual screening from January 2004 to October 2007 in Xuanwu hospital were classified and analyzed statistically. RESULTS： The ADR induced by traditional Chinese medicines appeared at different age group, possibly taking a big proportion in the causal relation appraisal. Injections took the lead among all the traditional Chinese drugs involved in ADR, and intravenous drip infusion was the major route of administration. The chief ADR involved systems/organs and manifested by lesions of skin and the appendants. CONCLUSION： Great importance should be attached to traditional Chinese medicine - induced ADR. The injections should be used rationally and the intravenous drip should be chosen prudently in medical treatment to reduce the incidence of ADR, speed up the transmission of the ADR information and ensure safe and rational medication.
出处
《中国医院用药评价与分析》
2009年第2期151-153,共3页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
中药不良反应
分析
合理用药
Traditional Chinese medicine ADR
Analysis
Rational drug use
