美洛西林钠致口腔多发性血疱1例

A case report of mezlocillin sodium-induced multiple oral mucosal bloody bullae

四川大学华西口腔医院黏膜科对1例药物性血小板减少性症(美洛西林钠相关性)患者给予糖皮质激素、成分输血治疗,使其病愈出院。本文还就药物性血小板减少症的诊断、易引起血小板减少的常见药物以及口腔血疱相关疾病的鉴别诊断进行了讨论。

This article reported a case of a 62-year old female patient of pneumonia whose emptysis appeared just three days after using mezlocillin, and afterwards mutiple oral bloody bullae were visible. The final clinical diagnosis defined that it was drug-induced thrombocytopenia （associated with mezlocillin）, and the patient was well-cured and left hospital two weeks after treated with glucocorticoid and blood component transfusion. This article discussed how drug-induced thrombocytopenia was diagnosed, what drugs likely inducing thrombocytopenia were and how diseases resulting in oral bloody bullae were distinguished.