灸百会 膻中和松弛疗法对抑郁症患者血浆五羟色胺的影响

Research on Influence of Moxibustion at Baihui,Shanzhong Points and Relaxing Therapy on Concentration of Major Depressive Disorder

目的:观察灸百会、膻中和松弛疗法对抑郁症患者血浆五羟色胺(5-HT)含量的影响。方法:将60例患者,按就诊先后随机分为治疗组(灸百会、膻中和松弛疗法组)、对照组(西药氟西汀组),各组8周为1个疗程;各组治疗前后分别测定汉密尔顿抑郁量表(HAMD)分值及血浆中5-HT的含量,用高效液相色谱法及电化学分析法检测治疗前后患者血浆5-HT的含量,通过对比治疗前后的HAMD分值及血浆5-HT含量的变化,统计临床数据。结果:灸法和松弛疗法可明显改善抑郁症患者HAMD的评分,其改善情况与单纯的西药组相当;生化指标5-HT含量治疗前、后用x-±s表示,组内均数比较有显著性差异,P(0.05。结论:灸百会、膻中和松弛疗法可提高抑郁症患者体内5-HT浓度,与西药氟西汀的疗效相当。

Objective：Moxibustion Baihui purpose of observation, in the Shan and relaxation therapy on patients with depression serotonin （5 -HT） content. Methods：60 patients, the treatment has randomly divided into treatment group （moxibustion Baihui ,in the Shan And relaxation therapy group） ,the control group（ Western medicine fluoxetine） ,the groups eight weeks for a course;treatment of each group were measured before and after the Hamilton Depression Scale （HAMD） and scores of plasma 5 - HT content ,With high-performance liquid chromatography and electrochemical analysis detected before and after treatment in patients with 5 - HT content, by comparing before and after the treatment and plasma HAMD score 5 - HT content of the Census and clinical data. Resuhs：Moxibustion and relaxation therapy can be significantly improved in patients with depression HAMD score, to improve the situation with a simple group of western medicine ; biochemical indicators 5-serotonin levels before and after treatment with x ± s said that the groups are relatively few There was significant difference,P 〈 O. 05. Conclusion：Moxibustion therapy and relaxing therapy can influence the 5 -HT concentration in serum of Major Depressive Disorder patients significantly, that is ,they can increase 5 - HT concentration in serum.