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Toll样受体介导的肠道免疫研究进展 被引量：2

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作者 刘洋 李晓芳 唐立
机构地区 大连医科大学微生态教研室
出处 《中国微生态学杂志》 CAS CSCD 2009年第3期278-281,284,共5页 Chinese Journal of Microecology
基金 国家"973"项目(2007CB513000)
关键词 TOLL样受体 肠道免疫
分类号 R378 [医药卫生—病原生物学]
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参考文献46

  • 1MARIAN R. Neutra. Current concepts in mucosal immunology V Role of M cell in traepithelial transport of antigen and pathogens to the mucosal immune system[ J]. Am J physiol, 1998,274 : G785-G791.
  • 2HASHIMOTO C. The Toll gene of Drosophila, required for dorsal-ventral embryonic polarity, appears to encode a transmembrane protein [J]. Cell,1988,52(2) :269-279.
  • 3MEDZHITOV R. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity[ J]. Nature, 1997,388 (6640) : 394-397.
  • 4MACPHERSON A J, HARRIS N L. Interactions between commensal intestinal bacteria and the immune system[ J]. Nat Rev Immunol,2004 ,4 (6) :478-.485.
  • 5CARIO E. Bacterial interactions with cells of the intestinal mueosa: Toll-like receptors and Nod2 [ J ]. Gut ,2005,54 (8) :1182-1193.
  • 6MOLLNES. Hypothesis: combined inhibition of complement and CD14 as treatment regimen to attenuate the inflammatory response [ J ]. Adv Exp Med Biol,2008,632:253-263.
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  • 8MEDZHITOV R. Recognition of microorganisms and activation of the immune response[J]. Nature,2007,449(7164) :819-826.
  • 9Epithelial-cell recognition of eommensal bacteria and maintenance of immune homeostasis in the gut[J]. Nat Rev Immunol,2008,8(6) :411-420.
  • 10SMITH K, McCOY K D, MACPHERSON A J. Use of axenic animals in studying the adaptation of mammals to their commensal intestinal microbiota [ J ]. Semin Immunol, 2007,19 (2) :59 -69.

同被引文献25

  • 1Belvin MP, Anderson KV. A conserved signaling pathway: the Dro- sophila toll-dorsal pathway [J]. Annu Rev Cell Dev Biol, 1996, 12: 393-416.
  • 2Jr Janeway CA, Medzhitov R. Innate immune recognition [ J ]. Annu Rev Immunol, 2002, 20 : 197-216.
  • 3West AP, Koblansky AA, Ghosh S. Recognition and signaling by toll-like receptors [ J ]. Annu Rev Cell Dev Biol, 2006, 22 : 409- 437.
  • 4Medzhitov R, Preston-Hurlburt P, Jr Janeway CA. A human homo- logue of t]ae Drosophila Toll protein signals activation of adaptive im- munity[J].Nature, 1997, 388(6640): 394-397.
  • 5Jang T, Park HH. Crystal structure of TIR domain of TLR6 reveals novel dimeric interface of TIR - TIR interaction for Toll-like recep- tor signaling pathway[J]. J Mol Biol, 2014, 426 (19) : 3305- 3313.
  • 6Akira S, Takeda K. Toll-like receptor signaling [ J ]. Nat Rev Immu- nol, 2004, 4 (7) : 499-511.
  • 7O' Neill L A. TLRs: Professor Mechnikov, sit on your hat [ J ]. Trends Immunol, 2004, 25(12): 6874593.
  • 8Adams S. Toll-like receptor agonists in cancer therapy [ J ]. Immunol Ther, 2009, 1(6) : 949-964.
  • 9Abu-Rish EY, Amrani Y, Browning MJ. Toll-like receptor 9 acti- vation induces expression of membrane-bound B-cell activating fac- tor(BAFF) on human B cells and leads to increased proliferation in response to both soluble and membrane-bound BAFF[ J]. Rheu- matology(Oxford) , 2013, 52(7) : 1190-1201.
  • 10Kumagai Y, Takeuchi O, Akira S. TLR9 as a key receptor for the recognition of DNA [ J]. Adv Drug Deliv Rev, 2008, 60 (7) : 795-804.

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二级引证文献1

中国微生态学杂志
2009年 第3期

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