甲状腺滤泡性肿瘤性质鉴别的分子标记物研究进展

Advances in tumor markers of distinguishing between benign and malignant follicular neoplasias

在临床实践中，甲状腺滤泡癌和甲状腺滤泡性腺瘤的鉴别诊断一直是一个难点。由于组织病理学经常难以诊断，因此需要一些分子标记物来帮助确定甲状腺滤泡性肿瘤的良恶性。本文将目前已发现的几种最新的能辅助甲状腺滤泡性肿瘤良恶性鉴别诊断的分子标记物，予以综述介绍。

A particular problem in clinical practice is the cytological differentiation between follicular thyroid carcinoma （FTC） and benign follicular thyroid adenoma （FTA）. Since the cell morphology is often nearly identical. Thus, diagnostic markers that would enable a better classification of follicular patterned lesions is necessary. In this article, we reviewed some novel molecular markers that high potential to improve dignoses of distinguishing between benign and malignant follicular neoplasias.