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LXRs与疾病

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摘要 肝X受体(LXRs)是核受体超家族的成员,包括两种亚型LXRα(NR1H3)和LXRβ(NR1H2)。LXRs被配体激活后,与类固醇X受体(RXRs)形成异源二聚体,再与其靶基因的LXR调控元件结合,通过调节靶基因的转录,调控机体的代谢和炎症反应。
作者 张锋 张玉梅
出处 《国外医学(卫生学分册)》 北大核心 2009年第2期101-105,共5页 Foreign Medical Sciences(Section of Hygiene)
基金 国家自然科学基金(30471449)
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