绝经后骨质疏松症体质因素的病例对照研究

Constitution factors for post menopausal osteoporosis:A case-control study

目的进行绝经后骨质疏松症相关体质因素研究。方法对224例绝经后骨质疏松症患者和238例非绝经后骨质疏松症者进行病例对照研究,体质判定标准采用《中医体质分类判定标准》。结果多元Logistic回归分析显示：在P〈0.05水平,最终进入回归方程的相关体质因素有4个：平和质、阳虚质、阴虚质、血瘀质,其中阳虚质、阴虚质,血瘀质为绝经后骨质疏松症发生的危险因素,且血瘀质在绝经后骨质疏松症的发病中相对重要;平和质为其保护因素。结论从体质角度探索绝经后骨质疏松症的发病机制是对其病因病机研究的补充。

Objective To investigate the constitution factors for Post Menopausal Osteoporosis（PMOP）. Methods 224 PMOP cases and 238 non-PMOP controls were selected.They were assessed according to the diagnosis standard of constitution of TCM.Results Multiple logistic regression analysis revealed that yang deficiency constitution、 yin deficiency constitution and blood-stasis constitution were dangerous factors for PMOP,normal constitution was protective factor for PMOP（P〈0.05）.Conclusion Research on constitution play a role in investigating pathogenesis of PMOP.