干扰素和易坦静联合治疗婴幼儿毛细支气管炎40例疗效观察

Effect of Interferon and Yitanjing on infants with bronchiolitis:40 cases observation

目的：探讨干扰素联合易坦静治疗婴幼儿毛细支气管炎的疗效。方法：80例毛细支气管炎患儿随机分为观察组和对照组，两组均给予吸氧、解痉平喘、镇静、祛痰等常规治疗，观察组在常规治疗的基础上采用干扰素联合易坦静进行治疗，比较两组临床症状消失时间以及x线胸片恢复情况。结果：观察组退热、止咳、平喘、肺部哮鸣音消失时间及总疗程较对照组明显缩短（P均〈0．01）。治疗后6～7dX线检查显示点状阴影恢复达90．0％，肺气肿征象恢复达80．0％，均明显高于对照组（分别为60．0％、55．5％）。结论：干扰素和易坦静联合治疗毛细支气管炎起效快、疗程短、疗效好，值得临床推广使用。

Objective： To explore the effect of Interferon and Yitanjing on infants with bronchiolitis. Methods： Randomly separated 80 infant patients with bronchiolifis into observation group and control group. Both groups were treated with regular therapy, such as oxygen inhalation, spasmolysis, antiasthmatic, sedation and ex- pectorant. Besides, patients in observation group were treated with interferon and Yitanjing. Compared disappea- ring time of clinical symptoms and X-ray status. Results： Comparing with control group, disappearing time of fever, cough, asthma and wheeze sound in lung, and total course in observation group significantly decreased. X-ray after 6-7d showed significant higher recovery rate of punctate shadow （ 90% ） and emphysema symptoms（ 80% ） in observation group than control group（60.0% and 55.5% respectively）, Conclusions： Combination therapy of interferon and Yitanjing has rapid effect, short course, and satisfactory efficacy. It is valuable in clinical application.