对多剂量眼用制剂不添加抑菌剂的思考

Consideration of preservative-free eye drops for multiple administrations

通过调研国内外多剂量眼用制剂抑菌剂的使用情况,针对多剂量眼用制剂中不添加抑菌剂的现象进行了分析;同时对抑菌功效试验的内容和意义进行了介绍。结合国内眼用制剂的生产条件、环境条件、患者的实际使用状况等,对多剂量眼用制剂不添加抑菌剂合理性进行了探讨。

After review of preservative use in eye drops for multiple administrations, the status of preservatire-free eye drops is analyzed in this article; the content and sense of tests for preservative effect are introduced as well. Considering manufacturing condition, environment and practical use, the rationality is discussed for preservative-free eye drops for multiple administrations.