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温石棉与香烟烟雾对人胚肺细胞产生H_2O_2的联合作用研究

The Study of Joint Effect of Chrysotile and Smoking on the Production of H 2O 2 in HEL Cells
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摘要 观察了温石棉与香烟烟雾溶液单独作用对人胚肺(HEL)细胞H2O2产生的影响,还采用3个析因设计,观察了不同剂量石棉与烟溶液同时作用下HEL细胞产生H2O2的变化情况。结果表明,当石棉与烟溶液单独作用时,均可使HEL细胞产生的H2O2量增多,当二者同时作用时,有两种联合方式表现为加强作用,另一种联合方式表现为相加作用,提示石棉为烟溶液联合作用剂量不同时,其联合作用结果也不同。 The single effects and joint effects of chrysotile and smoking solution on the production of H 2O 2 in HEL cells were studied.The results showed that chrysotile and smoking solution could increase the production of H 2O 2 in HEL cells,and there were obvious dosedependent relationship.Synergetical effects were found in two joint ways and additional effects was found in one joint way when chrysotile and smoking solution were added to HEL cells simultinuously,suggest that the results of joint effects were different with the change of concentration of chrysotile and smoking solution.
出处 《中国公共卫生学报》 1998年第2期117-118,共2页
关键词 温石棉 吸烟 过氧化氢 肺细胞 H2O2 Chrysotile Smoking H 2O 2
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参考文献2

  • 1吴卫东,中华预防医学杂志,1994年,28卷,272页
  • 2方允中,自由基与酶,1989年,51页

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