摘要
目的比较苯那普利与卡托普利对轻中度原发性高血压的降压效应与安全性。方法84例轻中度原发性高血压患者随机接受苯那普利(10~20mg/d)和卡托普利(37.5~75.0mg/d)(各42例)治疗4周,其中44例(每组22例)于治疗前后行24h动态血压监测。结果苯那普利和卡托普利的降压总有效率在偶测血压监测时分别为92.5%和90.5%(P>0.05),而动态血压监测时两药有效率分别为95.5%和63.6%(P<0.05)。结论苯那普利对轻中度原发性高血压疗效较好而且安全。
Aim To compared the effect of benazepril and captopril in treatment of hypertension. Methods Benazepril(10~20 mg/d) and captopril(37 5~75 0 mg/d) were given to two groups(each 44) of hypertensive patients for 4 weeks.Half of them were monitoring with ABPM. Results using causual blood pressure monitoring the effective rate were 90.5% in two groups( P >0.05).But by using ABPM, the benazepril group was 95.5%,whereas in the captopril group,the effective rate was only 63.3%( P <0.05). Conclusion Benazepril was more effective in treatment of hypertension.
出处
《高血压杂志》
CSCD
1998年第1期50-52,共3页
Chinese Journal of Hypertension