中药周期疗法对不孕患者子宫内膜形态学的影响

Effect of cycle therapy of traditional Chinese medicine on the morphology of endometrium in infertile women

目的观察中药周期疗法对不孕患者子宫内膜形态学的影响。方法排卵障碍性不孕患者随机分为中药周期治疗加克罗米酚组28例,克罗米酚组14例。予排卵前,优势卵泡直径≥18mm时,及排卵后7-8天进行阴道超声监测子宫内膜厚度、内膜形态类型。结果中药周期疗法加克罗米酚组与克罗米酚组内膜厚度、内膜类型、妊娠率比较,差异有统计学意义。结论中药周期疗法能改善因克罗米芬引起的抗雌激素作用的内膜厚度及类型,提高妊娠率。

Objective To assess the effect of cycle therapy of traditional Chinese medicine on the morphology of endometrium in infertile women. Methods 42 infertile women with anovulatory dysfunction were divided into two groups, one including of 14 patients were treated with clomiphene, and the other including of 28 patients were treated with cycle therapy of the traditional Chinese medicine based on clomiphene. The thickness and morphology of endometrium were examined by transvaginal ultrasound when dominant follicle diameter was larger than 18mm or equal to 18mm in pre - ovulation or post - ovulation for seven - eight days. Results There were significant differences between two groups in the thickness and morphology of endometrium, and the rate of pregnancy. Conclusion Cycle therapy of the traditional Chinese medicine can improve the thickness and morphology of endometrium, and hence increase the rate of pregnancy.