中西医结合治疗消化性溃疡的临床价值

The clinical value of of peptic ulcer treated with traditional Chinese medicine and Western medicine

目的探讨中西医结合治疗消化性溃疡的临床价值。方法89例消化性溃疡患者,随机分为治疗组及对照组。治疗组45例,给予柴胡桂枝汤加减,配合奥美拉唑(20mg,2次/d)、阿莫西林(750mg,2次/d),疗程4周;对照组44例,给予奥美拉唑(20mg,2次/d)和阿莫西林(750mg,2次/d),疗程4周。观察两组症状的缓解率及不良反应,并于疗程结束后复查胃镜,观察Hp根除率、溃疡有效率。结果治疗组Hp根除率为89.7%(35/39),对照组为68.6%(24/35)(χ2=5.116,P<0.05);治疗组和对照组症状缓解率和不良反应发生率分别为93.3%,11.1%和88.6%,20.5%,两组间无统计学差异(P>0.05);治疗组溃疡有效率为91.1%、对照组为72.7%,两组比较有显著性差异(χ2=5.099,P<0.05)。结论中西医结合治疗消化性溃疡其疗效优于单纯西医治疗,值得临床进一步推广。

Objective To investigate the clinical value of peptic Ulcer treated with traditional Chinese medicine and western medicine.Methods 89 patients with peptic ulcer were randomly divided into treatment group and control group.Treatment group（45cases） were administrated ChaiHuGuiZhi decoction combined with omeprazole（20 mg,twice a day） and amoxicillin（750 mg,twice a day） for 4 weeks; Control group（44 cases） were treated with omeprazole（20 mg,twice a day）,and amoxicillin（750 mg,twice a day） for 4 weeks. The clinical symptoms and side-effects were observed,and gastroscope was rechecked after finishing course of treatment in order to observe Hp eradication and ulcer effective rate.Results The Hp eradication rate of the treatment group was 89.7%（35/39）,while that of the control group was 68.6%（24/35）,There was significant difference between two groups（χ2=5.116,P〈0.05）.The symptomatic relief rate and side-effect rate between the treatment group and control group were 93.3% ,11.1% and 88.6%,20.5%,respectively,there was no diffierence between two groups（P〉0.05）.The ulcer effective rate of trement group was 91.1%,while that of the control group was 72.2%,There was statistically significant between two groups（χ2=5.099,P〈0.05）.Conclusion The therapeutic effect in conbined treatment of traditional Chinese medicine and western medicine is superior to that of single western medicine,which is worthy of being further spreaded in clinical practice.