同步间歇指令通气治疗足月新生儿呼吸窘迫综合征疗效观察

Use of synchronized intermittent mandatory ventilation in the treatment of neonatal ARDS

目的探讨同步间歇指令通气(SIMV)治疗足月新生儿呼吸窘迫综合征(ARDS)的优越性及其临床价值。方法对36例需要机械通气治疗的足月新生儿ARDS患儿采用SIMV模式,观察上机后的临床表现、动脉血气变化及并发症的发生。结果36例实施SIMV后,25例呼吸困难、紫绀明显缓解或消失,pH值、动脉血氧分压(PaO2)及达到某一PaO2所需的吸氧浓度(F iO2)均较治疗前有所提高,而动脉血二氧化碳分压较治疗前有所下降。30例(83.3%)ARDS患儿临床治愈,4例死亡,2例自动放弃治疗。结论SIMV模式对新生儿ARDS治疗效果较好,具有临床推广价值。

Objective To review the experience of using synchronized intermittent mandatory ventilation in treatment of neonatal ARDS. Methods Synchronized intermittent mandatory ventilation（ SIMV ） was used to treated 36 neonates with ARDS , clinical data including the clinical manifestation arterial blood - gas analysis and complications associated with ARDS were collected. Results Immediately after mechanical ventilation, dyspnea and cyanose of 25 patients alleviated or disappeared. Compared with pre- treatment, the pH, PaO2, PaO2/FiO2 were increased, and the PaCO2 was decreased. 30 patients were cured,4 patients died,2 patients abandoned treatment. Conclusion SIMV has good effect on ARDS of neonate.