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副脊索瘤3例报道并文献复习 被引量:3

Parachordoma:a report of 4 cases and review of literature
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摘要 目的探讨副脊索瘤临床病理学特点及其诊断与鉴别诊断。方法对报道的3例副脊索瘤进行临床资料分析、组织学形态和免疫表型观察并复习相关文献。结果副脊索瘤好发于四肢深部软组织。大体呈分叶状或多结节状,瘤细胞圆形或多边形,呈条索状或小巢状排列,胞质内含有空泡,间质富有黏液基质。免疫组化标记:CAM 5.2、EMA、S-100、SMA、ColⅣ阳性表达,CEA、CK19、Des阴性。结论副脊索瘤是一种少见的软组织肿瘤,组织学形态特点是其诊断的主要依据,免疫组化标记有助于诊断和鉴别。 Purpose To investigate the clinicopathological feature,diagnosis and differential diagnosis of parachordoma.Methods Three cases of parachordoma were studied by clinical data analyses,histopathology and immunohistochemistry.The related literature were reviewed.Results The tumors mainly occurred in the deep soft tissue of the limbs.Tumor was lobulated or multinodular.The neoplastic cells were round or polygon with vacuoles within the cytoplasma which arranged in nests or cords,and the stroma was rich in myxoid matrix.Immunohistochemically,the tumor cells were positive for CAM 5.2,EMA,S-100,SMA,collagen Ⅳ,and negative for CEA,CK19 and desmin.Conclusions Parachordoma is a rare soft tissue tumor,and its diagnosis mainly depends on histopathologic feature.Immunohistochemistry is helpful for the diagnosis and differential diagnosis.
出处 《临床与实验病理学杂志》 CAS CSCD 北大核心 2009年第5期491-493,共3页 Chinese Journal of Clinical and Experimental Pathology
关键词 副脊索瘤 诊断 鉴别诊断 免疫组织化学 parachordoma diagnosis differential diagnosis immunohistochemistry
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参考文献9

  • 1Dabska M.Parachordoma:a new clinicopathologic entity[J].Cancer,1977,40(4):1586-1592.
  • 2Spivach A,Zanconati F,Tirabosco R,et al.Parachordoma of the gastric serosa:report of a myxoid mimicry in an unusual location[J].Jnt Surg Pathol,2007,15(3):307-310.
  • 3王坚,朱雄增.软组织肿瘤病理学[M].北京:人民卫生出版社.2008:81-84,124-126.
  • 4Folpe A L,Agoff S N,Willis J,et al.Parachordoma is immunohistochemically and cytogenetically distinct from axial chordoma and extraskeletal myxoid chondrosarcoma[J].Am J Surg Pathol,1999,23(9):1059-1067.
  • 5Tihy F,Scott P,Russo P,et al.Cytogenetic analysis of a parachordoma[J].Cancer Genet Cytogenet,1998,105(1):4-19.
  • 6于鸿,王朝夫,朱雄增.骨外黏液样软骨肉瘤病理与鉴别诊断附4例报道并文献复习[J].临床与实验病理学杂志,2008,24(5):526-529. 被引量:9
  • 7李远,邓志平,刘文生,牛晓辉.副脊索瘤一例报告并文献综述[J].中国骨肿瘤骨病,2007,6(2):76-79. 被引量:3
  • 8Abe S,Imamura T,Harasawa A,et al.Parachordoma with multiple metastases[J].J Comput Assist Tomogr,2003,27(4):634-638.
  • 9雷玉涛.一例诊断困难的软组织副脊索瘤16年诊治体会[J].实用医学杂志,2005,21(22):2594-2595. 被引量:5

二级参考文献30

  • 1刘文丽,苏妩.右手掌软组织内副脊索瘤1例[J].诊断病理学杂志,2004,11(5):336-336. 被引量:1
  • 2C Fotiadis,A Charalambopoulos,S Chatzikokolis,GC Zografos,M Genetzakis,R Tringidou.Extraskeletal myxoid chondrosarcoma metastatic to the pancreas: A case report[J].World Journal of Gastroenterology,2005,11(14):2203-2205. 被引量:14
  • 3雷玉涛.一例诊断困难的软组织副脊索瘤16年诊治体会[J].实用医学杂志,2005,21(22):2594-2595. 被引量:5
  • 4[1]Laskowski J.Pathology of tumors,1955:91,99.
  • 5[2]Dabska M.Parachordoma:a new clinicopathologic entity.Cancer,1977,40:1586-1592.
  • 6[3]Abe S,Imamura T,Harasawa A,et al.Parachordoma with multiple metastases.J Comput Assist Tomogr,2003,27:634-638.
  • 7[4]Folpe AL,Agoff SN,Willis J,et al.Parachordoma is immunohistochemically and cytogenetically distinct from axial chordoma and extraskeletal myxoid chondrosarcoma.Am J Surg Pathol,1999,23:1059-1067.
  • 8[5]Scolyer RA,Bonar SF,Palmer AA,et al.Parachordoma is not distinguishable from axial chordoma using immunohistochemistry.Pathol Int,2004,54:364-370.
  • 9[6]Tihy F,Scott P,Russo P,et al.Cytogenetic analysis of a parachordoma.Cancer Genet Cytogenet,1998,105:14-19.
  • 10[8]Limon J,Babinska M,Denis A,et al.Parachordoma:a rare sarcoma with clonal chromosomal changes.Cancer Genet Cytogenet,1998,102:78-80.

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