炎症反应影响脑缺血再灌注损伤的研究进展

Inflammatory Reaction during Cerebral Ischemia Reperfusion Injury (review)

脑缺血再灌注损伤是脑损伤的因素之一,而局部过度炎症反应是造成再灌注损伤主要原因之一。许多炎症细胞及炎症介质均参与了炎症反应。本文主要综述炎症细胞、细胞因子、趋化因子、黏附分子等炎症因子对脑组织损伤的影响。

The cerebral ischemia reperfusion injury is one of factors in aggravating brain injury,and the inflammatory response is one of the main reasons in the reperfusion injury after acute cerebral ischemia.Inflammation is modulated by many factors such as inflammatory mediators and inflammatory cells that promote brain damage from ischemia injury to reperfusion injury.This paper would review the role of inflammatory cells and mediators such as cytokines,chemotactic factors,adhesion molecules on cerebral tissue injury.