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胃肠道间质瘤21例临床病理分析

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摘要 目的:探讨胃肠道间质瘤的临床病理及免疫组化特点。方法:对21例胃肠道间质瘤进行临床病理分析,并应用CD117、CD34、SMA、S-100以及V im抗体进行免疫组化染色。结果:镜下梭形细胞为主型14例(66.7%),上皮样细胞为主型5例(23.8%),混合细胞型2例(9.5%)。其中良性10例,潜在恶性4例,恶性7例,CD117阳性表达率85.7%(18/21)、CD34阳性率71.4%(15/21)。结论:胃肠道间质瘤是胃肠常见的间叶性肿瘤,缺乏定向分化。CD117和CD34阳性表达是诊断胃肠道间质瘤最可靠的辅助指标。
作者 李莉
出处 《青海医药杂志》 2009年第11期17-20,共4页 Qinghai Medical Journal
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  • 1施尧.胃肠道间质瘤的新概念和诊断[J].胃肠病学,2005,10(3):131-133. 被引量:19
  • 2谢铭.胃肠道间质细胞瘤预后因素分析[J].中国现代医学杂志,2006,16(10):1587-1588. 被引量:2
  • 3[1]Miettnen M,Riaia Ms.Gastrointestinal stromal tumor value of CD34 antigen in their identification and separation from true leiomyomas and schwannomass [J].Am J Surg pathol,1995,19(2):207-216.
  • 4[2]Kindblom LG,Remotti HE,Aldenborg F,et al. Dipact:gastrointestinal stromal tumors show phenotypics of the intestital cells of cajal[J]. Pathol,19 98,152(5):1259-1261.
  • 5[4]M miettinen SH,Leslie Maarit sarlow-Rikala.Immunohistochemical spectrum of GISTs at different sites and their differential diagnosis with a reference to CD117[J]. Modern Pathology, 2000,13(10):1134-1142.
  • 6Mazur MT, Clark HB. Gastric stromal tumors. Reappraisal of hitogenesis. Am J Surg Pathol, 1983, 7: 507-519.
  • 7Rosai J. Stromal tumors. In: Ackerman's surgical pathology. 8th ed. St. Louis: Mosby, 1996. 645-647.
  • 8Erlandson RA, Klimstra DS, Woodruff JM. Subclassification of gastrointestinal stromal tumors based on evaluation by electron microscopy and immunohistochemistry. Ultrastruct Pathol, 1996,20:373 -393.
  • 9Hirota S, Isozaki K, Moriyama Y, et al. Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors. Science, 1998,279:577-580.
  • 10Kindblom LG, Remotti HE, Aldenborg F, et al. Gastrointestinal pacemaker cell tumor(GIPACT) :gastrointestinal stromal tumors show phenotypic characteristics of the interstitial ceils of Cajal. Am J Pathol, 1998,152 : 1259-1269.

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