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玉米浆对林可链霉菌的代谢特性及形态的动态影响 被引量:2

Dynamic effects of corn steep liquor on metabolic characteristics and mycelium morphology of Streptomyces lincolnensis
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摘要 菌丝形态的定量计算表明,添加玉米浆后,茵团核心面积、菌丝面积、圆形因子和边缘茵丝密度等形态学参数均呈上升趋势,菌丝形态得到明显改善,中后期和后期的平均比生长速率增大,茵体的维持代谢和次级代谢保持在较高较稳定水平,有效解决了中后期及后期林可链霉菌的比生长速率为负及林可霉素产量的增长幅度很小的问题。 The quantitative calculation of parameters on morphology indicated that after adding corn steep liquor(CSL), the core area of mycelium cluster, mycelial area, circularity and roughness were all in increasing trend; the state of mycelium was significantly improved; the specific growth rates(μ) of mid-late and later stage were increased. Thus the high maintenance and secondary metabolism of Streptomyces lincolnensis were achieved, and the problems that μ was negative and small increase rate of lincomycin production in later period were solved effectively.
出处 《工业微生物》 CAS CSCD 2009年第6期16-19,共4页 Industrial Microbiology
关键词 林可链霉菌 林可霉素 发酵 形态学 Streptomyces lincolnensis lincomycin fermentation morphology
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  • 1叶万荣.旋光法测定发酵液中林可霉素的含量[J].医药工业,1987(2):76-77. 被引量:2
  • 2孟娜,吴丁柱,李婉珍,魏胜华.林可霉素高产菌株的定向选育[J].发酵科技通讯,2013,42(4):9-12. 被引量:4
  • 3北京大学生物系生化教研室.生物化学实验指导[M].北京:高等教育出版社,1986.
  • 4李殡.多元萃取体系提取林可霉素的热力学研究[D].河北:河北工业大学,2004:10-11.
  • 5Rajeswaran M, Srikrishnan T. Crystal and molecular struc- ture and absolute configuration of lincomycin hydrochlo- ride monohydrate [ J ]. Carbohydr Res, 2004,339 ( 12 ) : 2111-2115.
  • 6Olsovska J,Jelinkova M,Man P. ttigh-through put quanti- fication of lincomycin traces in fermentation broth of genet- ically modified streptomyces spp. comparison of ultra per- formance liquid chromatography and high-performance liq- uid chromatography with UV detection [ J ]. Journal of Chromatography A ,2007,1139:214-220.
  • 7Spizek J, Rezanka T. Lincomycin, cultivation of producing strains and biosynthesis [ J ]. Applied Microbiology and Biotechnology, 2004,63 (5) :510-519.
  • 8Gerasimova S, Berezina E. Cytomorphological study of lin- comycin toxicity [ J ]. Antibiotiki, 1977,22 (6) : 539.
  • 9何家骏,樊世从.液化糖代替葡萄糖在林可霉素发酵中的应用[J].中国医药工艺杂志,1992,23(7):296.
  • 10薛正莲,朱艳,张相美,潘文洁.响应面法优化林可霉素发酵培养基[J].中国抗生素杂志,2009,34(5):277-280. 被引量:6

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