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二甲双胍对高胰岛素血症儿童假性黑棘皮病的疗效观察 被引量：1

Effect of metformin on children with hyperinsulinemia and acanthosis nigricans
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摘要 对88例高胰岛素血症假性黑棘皮病（AN）肥胖儿童给予二甲双胍治疗3个月和6个月后，对空腹胰岛素、葡萄糖耐量试验2h胰岛素和AN评分等进行评价，结果表明二甲双胍可改善假性AN肥胖患儿高胰岛素血症状态，AN分级方法可作为病情变化的无创监测手段。 Tatal 88 obese children with hyperinsulinemia and acanthosis nigricans （AN） were given metformin for 3 and 6 months. The levels of fast insulin,2 h postprandial insulin, and AN score were lower after treatment. Metformin therapy on obese children with hyperinsulinemia and AN was safe. AN score may be an appropriate non-invasive index monitoring disease prognosis.
作者 姜丽红 刘戈力 杨菁岩 马成成
机构地区 天津医科大学总医院儿科
出处 《中华内分泌代谢杂志》 CAS CSCD 北大核心 2009年第6期628-630,共3页 Chinese Journal of Endocrinology and Metabolism
关键词 二甲双胍 假性黑棘皮病 高胰岛素血症 肥胖症 儿童 Metformin Acanthosis nigricans Hyperinsulinemia Obesity Children
分类号 R587.1 [医药卫生—内分泌] R977.15 [医药卫生—药品]
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参考文献12

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二级参考文献36

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共引文献2027

同被引文献19

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中华内分泌代谢杂志
2009年 第6期

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