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Toll样受体介导的抗乙型肝炎病毒免疫应答

Immune response of TLRs mediated anti-hepatltis B virus
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摘要 Toll样受体(TLRs)在抗病毒固有免疫应答中起着重要作用,并指导和调节适应性免疫庄答。HBV是引起慢性病毒性肝炎的主要病原体,其引起慢性乙型肝炎的机制尚不清楚。此文对TLRs介导的同有免疫应答与慢性乙型肝炎的发生及其在抗HBV中所起的作用和机制作了综述。 Toll-like receptors(TLRs) play an important role in antiviral innate immunity and modulate the adaptive immunity. HBV is the main pathogen to cause chronic hepatitis B and its pathogensis mechanism is still unclear. In the article, recent advances of the TLRs mediated innate immunity and its role in anti-HBV immunity are reviewed.
出处 《国际流行病学传染病学杂志》 CAS 2009年第6期424-427,共4页 International Journal of Epidemiology and Infectious Disease
基金 浙江省自然科学基金(Y207534)
关键词 肝炎病毒 乙型 TOLL样受体 固有免疫 Hepatitis B virus Toll-like receptor Innate immunity
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