摘要
目的观察中药复方慢肝消对酒精性肝病的治疗效果.方法酒精性肝病92例,分治疗组64例,对照组28例.治疗组用慢肝消,对照组用加味逍遥散.治疗组和对照组中脂肪肝分别为13例(120%)和9例(321%),肝炎分别为19例(277%)和6例(321%),肝硬变分别为22例(344%)和9例(321%),混合型各为10例(156%)和4例(143%).临床主要表现为纳呆、腹胀、胁胀或痛,呕恶便溏,乏力.3mo1疗程,观察结束后,对症状、体征、肝功能、胶原代谢,及免疫功能等方面的变化进行分析研究.结果治疗组临床治愈5例,显效36例,好转19例,无效4例,总有效率为938%,对照组临床治愈0例,显效12例,好转8例,无效8例,总有效率为714%.结论慢肝消具有改善肝功能,抗肝纤维化,调解免疫功能的作用。
AIM To observe the therapeutic effect of traditional Chinese medicine decoction Manganxiao in alcoholic liver diseases. METHODS Ninety two patients with alcoholic liver diseases were treated with Manganxiao for 3 months. They were divided into treatment group (64 cases) and control group (28 cases). Traditional Chinese medicine decoction Manganxiao was used in treatment group, and traditional Chinese medicine decoction Xiaoyaosan was used in control group. In these two groups,there were 13(12%)and 9(32.1%) patients with fatty liver;19 (27 7%) and 6 (21 4%) hepatitis;22 (34 4%) and 9 (32 1%) cirrhosis;and 10 (15 6%) and 4 (14 3%) mixed types. The clinical manifestations were anorexia, abdominal distension, distension or pains of the hypochondrium, nausea, loose stool and feebleness. One course of treatment was three months. After treatment, the changes of patients' symptoms, signs, liver function, changes of collagen and the improved function of immunity were studied and analysed. RESULTS After 3 month treatment with Manganxiao in treatment group, 5 patients were recovered, 36 effective, 19 improved, and 4 ineffective with a total efficacy rate of 93 8%. In control group, no patient was recovered, 12 effective, 8 improved, and 8 ineffective with a total efficacy of 71 4%. CONCLUSION Manganxiao can improve liver function and the function of immunity and constitution and resist fibrosis.
基金
国家教委博士点学科点基金
关键词
中医药疗法
肝疾病
酒精性
肝硬化
中草药
liver diseases, alcoholic/therapy
liver cirrhosis/therapy
drugs, Chinese herbal