摘要
目的:对肾移植超急性排斥反应(HAR)的发生机制、危险因素、诊断与鉴别诊断、预防及处理进行分析。方法:1978年6月~1997年12月施行同种异体肾移植1500例,发生HAR64例(4.27%)。结果:除1例对症处理外,其余移植肾均于术中或术后短期予以摘除,对15例在短期内作了再次移植,10例(66.7%)取得成功。结论:HAR是一种严重的不可逆性体液排斥反应,目前对其治疗尚无良策,一旦发生应尽早切除移植肾,近期内可行再次移植。
OBJECTIVE To report our experience of 64 cases of hyperacute rejection after renal transplantation. METHODOLOGY 64 renal recipients in whom hyperacute rejection occurred were included in this study.The clinical and pathologic data were analyzed retrospectively. RESULTS The rate of hyperacute rejection in our group of renal allograft recipients was 4 27%(64/1500).Allograft nephrectomy was performed except in one patient.Among these 64 patients,15 had re transplantation in near term,and the re transplanted grafts survived in 10 patients. CONCLUSION Hyperacute rejection is one form of sever irreversible humoral mediated rejection.There is no effective treatment once it occurred and the graft should be removed.Retransplantation in near term is effective in some patients.
出处
《肾脏病与透析肾移植杂志》
CAS
CSCD
1998年第5期433-435,共3页
Chinese Journal of Nephrology,Dialysis & Transplantation
关键词
肾移植
排斥反应
急性
再次移植
kidney transplantation hyperacute rejection re transplantation