264例性病门诊患者泌尿生殖道支原体感染调查及药敏分析

Urinogenital mycoplasma infection and drug-susceptibility in outpatients with social disease

目的了解南京地区近年性传播疾病(STD)门诊患者泌尿生殖道支原体感染及耐药情况。方法采用珠海丽珠试剂有限公司生产的解脲支原体(Uu)和人型支原体(Mh)分离、鉴定、计数、药敏试剂盒检测患者泌尿生殖道分泌物,然后分析就诊患者的支原体培养及药敏试验结果。结果264例患者中支原体阳性123例,感染率为46.6%。其中Uu、Mh和Uu+Mh感染的阳性结果分别为99例(37.5%)、6例(2.3%)、18例(6.8%)。药敏试验结果显示,3组患者都对美满霉素(MIN)和强力霉素(DOX)敏感。结论支原体感染已成为泌尿生殖道感染的主要病原体之一,主要为Uu引起,占80.5%(99/123),美满霉素和强力霉素是治疗泌尿生殖道支原体感染的首选药物。

Objective To determine the urinogenital mycoplasma infection and drug resistance in outpatients with social disease in Nanjing areas. Methods The urinogenital tract secretions of outpatients were detected by ureaplasma urealyticum（Uu）and macoplasma hominics （Mh） test kits, and the mycoplasma culture and the drug suscep tibility test were analyzed. Results 123 of 264 cases were infected with myeoplasma （positive rate 46. 6%）,99 patients were infected with Uu （37.50/00）,6 patients were infected with Mh （2.3%）,and 18 patients were coinfected with Un and Mh （6.8%） ,respectively. By drug susceptibility test,MIN and DOX were susceptibility for all patients in three groups. Conclusion Mycoplasma is a general pathogens for the patients with urinogenital infection,and MIN and DOX may be applied to first treatment of urinogenital mycoplasma infection.