慢性肾脏病并发症治疗现状及思考

Complications of chronic kidney disease:current management and challenge

慢性肾脏病(CKD)已经成为影响公众健康的重要疾病。无论接受替代治疗与否,各种并发症如控制不当都将导致CKD患者预后不良和过早死亡,其中心脑血管并发症是最重要原因。CKD并发症的发生时间可能较预想的要早。应重视对其早期发现、积极干预、定期监测并及时调整治疗方案。基于循证医学研究制定的临床指南对于指导CKD并发症的治疗具有重要意义,同时也应注意个体化治疗,以提高患者存活率、改善生活质量,使之更好地回归社会。

Chronic kidney disease （CKD）is increasingly recognized as a global public health problem. Uncontrolled complications of CKD, especially cardiovascular diseases, contribute greatly to the premature death and unfavorable prognosis. Recent evidence shows that CKD complications may occur earlier than previously thought. CKD complications deserve early detection and active treatment. Periodical follow-up and regular check should be done to adjust the therapeutic condition. Clinical practice guideline or recommendation based on evidence-based medicine is essential for management of CKD complications. Personalized treatment should be considered to improve survival and quality of life,and to make patient return to society.