期刊文献+

高血压患者脉压指数与血浆内皮素-1的关系 被引量:2

Relationship between pulse pressure index and endothelin-1(ET-1) in patients with essential hypertension
下载PDF
导出
摘要 目的:探讨原发性高血压病(EH)患者的脉压指数(PPI)与血浆内皮素一1(ET一1)的相互关系。方法:146例EH患者,行24h动态血压监测,计算PPI值,根据PPI值分为三组,PPI〈0.35为A组,PP10.35~0.45为B组,PPI〉0.45为C组。正常体检者64例为对照组(D组)。四组研究对象均抽血化验血浆ET一1。结果:与对照组相比高血压患者血浆ET一1明显增加(P〈0.05)。而EH患者随着PPI的增加,ET—1增加更明显(P〈0.05),相关分析显示PPI与ET—1呈正相关(P〈0.01)。结论:EH患者PPI和血浆ET一1明显增加。 Objective:To observe the relationship between pulsepressure index(PPI) and endothelin 1 (ET-1) in patients with essential hypertension (EH). Methods:Tenty-four hours ambulatory blood pressures (24 h APP)were monitored. 146 patients were divided into three groups according to the level of PPI :PPI0.35 were defined group A. PPI 0.35~0.45 were defined group B. PPI〉0. 45 were defined group C. 64 normal people were defined group D,contrast group. All patients selected and normpeople was observed their levels of plasma endothelin-1 (ET-1). Results: There were significant increases in plasma ET-1 in patients with EH compared with contrast group(P〈0.05). In patients with EH,the ET-1 were significantly different among the subgroups of PPI (P〈0.05). The ET-1 were positive- ly correlated to the PPI(P〈0.01). Conclusion:There were significant increases PPI and in plasma ET-1 in patients with EH.
出处 《临床医药实践》 2010年第2期98-99,共2页 Proceeding of Clinical Medicine
关键词 原发性高血压 脉压指数 内皮素-1 essential hypertension tpulse pressure index endothelin-1
  • 引文网络
  • 相关文献

参考文献5

  • 1Mitchell G F,Moye L A,Braunwald E,et al. Sphygmomanometrically determind pulse pressure is a powerful independent predictor of recurrent events after myocardial infarction in patients with impaired left ventricular function[J]. Circulation, 1997,96 (4) 4 254-4 260.
  • 2Sesso H D,Stanipfer M J ,Rosner B,et al. Sytolic and diastolic blood pressure, pules pressure, and predictors of cardiovascular disease risk in men[J].Hypertension, 2000,36 (5) : 805-807.
  • 3Mceniery C M,Wallace S,Mackenzie Z S,et. al. Endothelial function is associated with pulse pressure, pulse wave velocity, and augmentation index in health humans [J]. Hypertension, 2006,48 (4) : 604- 608.
  • 4汪克纯,李家富.高血压患者脉压和脉压指数与血管内皮功能的关系[J].中国心血管杂志,2006,11(4):271-274. 被引量:16
  • 5石洁,胡元会,商秀洋,王阶,高改地,宋庆桥.老年原发性高血压患者颈动脉病变与动态脉压指数[J].中华高血压杂志,2008,16(3):213-215. 被引量:16

二级参考文献13

共引文献30

同被引文献17

引证文献2

二级引证文献18

;
使用帮助 返回顶部