期刊文献+

脑血管病与血浆同型半胱氨酸水平的关系研究 被引量:5

下载PDF
导出
摘要 脑血管病是由于供应脑组织的血管发生病变所导致的疾病,常伴有偏瘫、失语、偏盲、意识障碍甚至昏迷。在我国,脑血管病的病死率占第二位,大约为20%。据统计脑出血的死亡率是37%~50%。而脑血管病的幸存者则残留下轻重不等的偏瘫、失语和痴呆等残疾,给患者、家属和社会带来了沉重的负担。脑血管病的危险因素包括高血压、高脂血症、糖尿病、高黏滞血症、吸烟、饮酒及年龄等,
出处 《中华老年心脑血管病杂志》 CAS 北大核心 2010年第2期180-181,共2页 Chinese Journal of Geriatric Heart,Brain and Vessel Diseases
  • 相关文献

参考文献3

二级参考文献26

  • 1王宁,谢自敬,阿不力克木,易兴,苏联群.乌鲁木齐新市区30岁以上汉族群体2 687人血脂流行病学调查[J].中国临床康复,2005,9(15):4-6. 被引量:5
  • 2Lonn E,Yusuf S,Arnold MJ,菅鑫妍.血管疾病中叶酸和B族维生素的使用不能降低高半胱氨酸浓度[J].中国处方药,2006,5(6):23-24. 被引量:136
  • 3李永杰,付伟,刘颖,刘菊红,杨铁生,李丰升,高旭光.老年脑梗死患者血浆同型半胱氨酸水平及相关因素研究[J].中华老年心脑血管病杂志,2006,8(7):459-461. 被引量:21
  • 4各类脑血管疾病诊断要点[J].中华神经科杂志,1996,29(6):379-380. 被引量:33037
  • 5Sauls DL, Wolberg AS, Hoffman M. Elevated plasma homocysteineleads to alterations in fibrin clot structure and stability: implicationsfor the mechanism of thrombosis in hyperhomocysteinemia[J]. Journalof Thrombosis and Haemostasis,2003,1:300-306.
  • 6Majors AK, Sengupta S, Jacobsen DW, et al. Upregulation of smoothmuscle cell collagen production by homocysteine-insight into thepathogenesis of homocysteinuria[J]. Mol Genet Metab, 2002,76:92-99.
  • 7Zhou J, Moller J, Danielsen CC, et al. Dietary supplementation with methionine and homocysteine promotes early atherosclerosis but notplaque rupture in ApoE-deficient mice[J]. Arterioscler rlhromb VascBiol, 2001,21:470-476.
  • 8Au-Yeung KK, Woo CW,Sung FL, et al. Hyperhomocysteinemia ac-tivates nuclear factor-κB in endothelial ceils via oxidative stress[J].Grc Res,2004.94:28-36.
  • 9Tayama J, Munakata M, Yoshinaqa, et al. Higher plasma homoeys-teine concentration is associated with more advanced systemic arterial stiffness and greater blood pressure response to stress in hypertensive patients[ J ]. Hypertens Res, 2006,29 : 403-409.
  • 10Garcia-Pinilla JM, Espinosa-Caliaui S, Gomey-Doblas JJ, et al. Influence of high homocysteine and low folate plasmatic levels in mediumterm prognosis after acute coronary syndromes [ J ]. Int J Cardiol, 2006,162:1007-1010.

共引文献175

同被引文献38

  • 1范红燕,吴素慧.同型半胱氨酸在绝经期妇女冠心病预防中的作用[J].山西医科大学学报,2005,36(2):241-243. 被引量:8
  • 2樊东升.预防脑卒中要重视对高同型半胱氨酸水平的控制[J].中华老年医学杂志,2005,24(4):309-309. 被引量:25
  • 3徐志红,陆国平,吴春芳.同型半胱氨酸对大鼠血管平滑肌细胞增殖及胶原生成的影响[J].中华老年心脑血管病杂志,2007,9(1):45-48. 被引量:22
  • 4Hackett ML, Carter G, Crimmins D,et al. Improving outcomes after stroke clinical pilot trial protocol. Int J Stroke, 2010,5(1): 52 -56.
  • 5Nestler EJ, Barrot M, DiLeone RJ, et al. Neurobiology of depression. Neuron,2002,34(1): 13-25.
  • 6Bottiglieri T, Laundy M, Crelin R, et al .Homocysteine folate methylation and monoamine metabolism in depression.J Neurol Neurosurg Psychiatry, 2000, 69(2): 228-232.
  • 7Ren C, Du A, Li D, et al. Dynamic change of hydrogen sulfide during global cerebral ischemia-reperfusion and its effect in rats. Brain Research, 2010, 1345(23): 197-205.
  • 8Shao JL, Wan XH, Chen Y, et al. H2S protects hippocampal neurons from anoxia-reoxygenation through cAMP-mediated PI3K/ Akt/p70S6K cell-survival signaling pathways- J Mol Neurosci, 2011,43(3):453-460.
  • 9Kimura H. Hydrogen sulfide induces cyclic AMP and modulates the NMDA receptor. Biochem Biophys Res Commun, 2000, 267(1): 129-133.
  • 10Lippi G,Plebani M. Hyperhomocysteinemia in health and disease: where we are now,and where do we go from here?[J]. Clin Chem Lab Med, 2012,50 (12) : 2075-2080.

引证文献5

二级引证文献22

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部