针刺对中风患者血浆过氧化脂质与6-K-P、TXB_2、6-K-P/TXB_2的相关性研究

Study on Correlativity between Plasma Lipid Peroxide and 6- K- P,TXB_2 ,6- K- P/ TXB_2 in Patients of Apoplexy Treated with Acupuncture

随机对 2 0例患者进行直线相关分析。结果证实 :针刺中风全疗程中 ,随临床症状、记忆力、体征康复同时 ,血浆高 LPO含量下降、6 -K-P含量上升、6 -K-P/TXB2 比值 (第 15天 )上升 ,均有极显著意义 (P<0 .0 0 1) ,直线相关统计分析呈现显著负相关性 (P<0 .0 0 1) ,TXB2 无显著差异。提示针刺在不影响 TXB2 原有水平基础上 ,调节了机体对氧自由基失衡的作用并及时促进 6 -K-P含量的升高和 6 -K-P/TXB2 比值的升高 ,这可能是针刺治疗中风和其它相关疾病取得临床疗效最重要的机理。

L inear correlation analysis was made randomly in 2 0 cases of apoplexy.Results indicated that in the com- plete course of acupuncture treatment of apoplexy, with recovery of clinical symptoms,memory and physi- cal signs,the higher content of plasma lipid peroxide ( LPO) decreased,6- K- P level and 6- K- P/ TXB2 ratio increased at the15th day with statistically very signifi- cant difference( P<0 .0 0 1) ;linear correlation analysis showed negative correlation( P<0 .0 0 1) and TXB2 con- tent did not have significant change.It is suggested that acupuncture does not influence original level of TBX2 and regulates imbalance of oxygen free redical in the organism and accelerates in time increase of6- K- P content and 6- K- P/ TXB2 ratio.This may be the most importantmechanism of acupuncture treating apoplexy and other relative diseases.