摘要
将三(苯基氨基甲酸)支链淀粉酯涂敷在硅胶上制成了手性固定相.将支链淀粉与过量的苯异氰酸酯在吡啶中反应得到的苯基氨基甲酸酯溶解并涂敷在用3-氨基丙基三乙氧基硅烷处理过的硅胶上,涂敷量为0.45/2.55(重量比).用此手性固定相拆分了外消旋的簇合物μ-FcCCHCoW(CO)5(CpCOOC2H5).拆分在室温下进行,洗脱液为甲醇,流速为0.5mL/min.
Amylopectin tris(phenylcarbamate) was synthesized and used as the chiral stationary phase upon adsorbed over silica gel. For this purpose, amylopectin was allowed to react with an excess of phenylisocyanate in pyridine for 48 h. The carbamate was dissolved and adsorbed on silica gel which had been treated with 3 aminopropyltriethoxysilane. The weight ratio of the carbamate to the silica gel was 0.45∶2.55. The racemic μ FcC CHCoW(CO) 5 (CpCOOC 2H 5) prepared from μ FcC CHCo 2(CO) 6 and (C 2H 5OOCCp)W(CO) 3Na was resolved on this chiral stationary phase. Separation was carried out at room temperature, and methanol was used as the eluent at a flow rate of 0 5 mL/min .
出处
《高等学校化学学报》
SCIE
EI
CAS
CSCD
北大核心
1998年第9期1397-1400,共4页
Chemical Journal of Chinese Universities
基金
中国科学院兰州化学物理研究所所长基金