摘要
Ｄ－（一）－苯甘氨酸是半合成氨苄青霉素，头孢氨苄，头孢克罗等β－内酰胺类抗生素的重要中间体，其经典的制备方法是用苯甲醛和氰化物加成再水解，即经ｓｔｒｅｃｋｅｒｓ反应合成［１］。该方法存在成本高，毒性大等缺点。七十年代后期到八十年代，由乙醛酸路线制备Ｄ...
In this paper,N Acetylphenylglycine is synthesized in high yield by using acetic anhydride as a catalyst,the concentration of glyoxylic acid being reduced.
出处
《化学研究与应用》
CAS
CSCD
1998年第6期661-662,共2页
Chemical Research and Application
